Booster vaccines may well offer good protection in the face of the Omicron variant, experts behind a major new study have suggested.
A team studying the effects of third doses said the body’s T cell immune response after a booster shot is such that it may provide protection from hospital admission and death.
The study also backs up the UK’s decision to offer Pfizer or Moderna as a third shot, with mRNA jabs leading to the most significant rise in immunity levels.
Professor Saul Faust, trial lead and director of the NIHR Clinical Research Facility at University Hospital Southampton NHS Foundation Trust said the CovBoost study had shown that six different vaccines are safe and effective as booster doses for people who have already had two doses of AstraZeneca or Pfizer/BioNTech.
The six vaccines tested as a third dose were AstraZeneca, Pfizer/BioNTech, Moderna, Novavax, Janssen (made by Johnson and Johnson) and CureVac (which has ceased production).
“All of the vaccines in our study do show a statistically significant boost… RNA (Pfizer and Moderna) very high, but very effective boosts from Novavax, Janssen and AstraZeneca as well,” Prof Faust said.