CategoryChina

China’s experimental COVID-19 vaccine appears safe – study

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A Chinese experimental coronavirus vaccine being developed by the Institute of Medical Biology under the Chinese Academy of Medical Sciences was shown to be safe in an early stage clinical trial, researchers said.

In a Phase 1 trial of 191 healthy participants aged between 18 and 59, vaccination with the group’s experimental shot showed no severe adverse reactions, its researchers said on Tuesday in a paper posted on medRxiv preprint server ahead of peer review.

The most common adverse reactions reported by the trial participants were mild pain, slight fatigue and redness, itching and swelling at the injection site.

The candidate also induced immune response.

“All the data obtained in this trial support the safety and immunogenicity of this inactivated vaccine and are encouraging with regard to further studies of its efficacy in the future,” the paper said.

https://www.reuters.com/article/health-coronavirus-china-vaccine/chinas-experimental-covid-19-vaccine-appears-safe-study-idUSL4N2GY0U5HELP US SPREAD GOOD NEWS!

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China in talks with WHO over assessing its COVID-19 vaccines for global use

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China is in talks to have its locally-produced COVID-19 vaccines assessed by the World Health Organization, as a step toward making them available for international use, a WHO official said on Tuesday.

Hundreds of thousands of essential workers and other groups considered at high risk in China have been given locally-developed vaccines even as clinical trials had not been fully completed, raising safety concerns among experts.

Socorro Escalate, WHO’s coordinator for essential medicines and health technologies in the Western Pacific region, told a news conference conducted online that China had held preliminary discussions with WHO to have its vaccines included in a list for emergency use.

https://www.reuters.com/article/us-health-coronavirus-who-china/china-in-talks-with-who-over-assessing-its-covid-19-vaccines-for-global-use-idUSKBN26R19BHELP US SPREAD GOOD NEWS!

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China Greenlights Another Covid-19 Vaccine for Human Testing

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A Chinese drugmaker, which is collaborating with AstraZeneca PLC on production of a coronavirus vaccine, has won approval from Chinese regulators to start testing one of its own vaccine candidates at home.

Shenzhen Kangtai Biological Products Co., one of the world’s largest producers of hepatitis B vaccines, said Tuesday in a stock-exchange filing it will begin testing its coronavirus vaccine candidate on people immediately, after it was found to protect mice and monkeys from the new virus.

The company, based in the southern Chinese city of Shenzhen, didn’t say where it would conduct the trials. Because China has largely brought the virus under control at home, its drugmakers have had to venture to other countries where coronavirus is still a problem to run larger scale advanced clinical trials. Their initial trials to test for safety, however, have generally taken place in China.

Shenzhen Kangtai also said it has already built a new facility for producing the vaccine, for which it will seek separate regulatory certification.

https://www.wsj.com/articles/china-greenlights-another-covid-19-vaccine-for-human-testing-11601445463HELP US SPREAD GOOD NEWS!

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Covid Antibodies Endure Over Six Months in China Trial Subjects

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The amount of Covid-19 antibodies in trial subjects who received China’s experimental vaccines remained high six months after the first shots, said a top Chinese scientist, projecting confidence that the country will be among the first to produce effective inoculation against the coronavirus.

The high levels detected in volunteers who took part in the earliest clinical trials suggest that the shots are effective and can provide immunity against the virus for an extended period of time, though final-stage testing results still need to be evaluated, Zeng Guang, chief scientist of the Chinese Center for Disease Control and Prevention, said in a briefing in Beijing on Friday.

Tianjin-based CanSino Biologics Inc, which is co-developing a coronavirus shot with the Chinese military, was the first in the world to administer an experimental vaccine into healthy people in March, though Zeng did not specify which vaccine candidate he was referring to.

China now has at least 10 vaccine candidates in human trials, with four in the final stages of Phase III testing around the world.

https://www.bloomberg.com/news/articles/2020-09-25/covid-antibodies-endure-over-six-months-in-china-trial-subjectsHELP US SPREAD GOOD NEWS!

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No new locally transmitted Covid-19 cases in China

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No new locally transmitted Covid-19 cases were reported Wednesday (Sept 23) across the Chinese mainland, the National Health Commission said Thursday.

Meanwhile, seven confirmed Covid-19 cases arriving from outside the mainland were reported, the commission said in its daily report.

No new suspected Covid-19 cases or new deaths related to the disease were reported, the commission said.

On Wednesday, eight Covid-19 patients were discharged from hospitals after recovery on the Chinese mainland.

https://www.thestar.com.my/aseanplus/aseanplus-news/2020/09/24/no-new-locally-transmitted-covid-19-cases-in-chinaHELP US SPREAD GOOD NEWS!

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Chinese state-backed firm expects coronavirus vaccine approval for public use within months

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State-backed vaccine maker China National Biotec Group (CNBG) is hopeful of two of its novel coronavirus vaccine candidates receiving conditional regulatory approval for general public use within the year, its vice president said on Tuesday.

China has inoculated hundreds of thousands of people under an emergency programme authorised in July for essential workers and other limited groups of people considered at high risk of infection, to stave off a resurgence of the coronavirus, even as clinical trials of vaccines are still underway to prove their efficacy and safety.

Inoculating the general public with a workable vaccine is likely to be an important tool in curbing a virus that has led to over 960,000 deaths worldwide. However, expanding vaccine use prior to obtaining long-term data risks raising expert concern.

“CNBG is discussing with relevant state authorities about the requirements for conditional approvals of the two coronavirus vaccines,” Zhang Yuntao told Reuters.

The South China Morning Post first reported CNBG’s talks with regulators.

“If all goes well, the two vaccines could hopefully be approved conditionally within the year for use in the general public,” Zhang said in a statement to Reuters.

https://www.reuters.com/article/us-health-coronavirus-cnbg-vaccines/chinese-state-backed-firm-expects-coronavirus-vaccine-approval-for-public-use-within-months-idUSKCN26D0TOHELP US SPREAD GOOD NEWS!

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Hundreds of thousands have been given Chinese COVID-19 vaccines without a single infection

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Hundreds of thousands of people have been given two Chinese COVID-19 vaccine candidates as part of an emergency program, without a single case of infection or adverse effects, a senior official of a state-owned vaccine developer has said.

The two vaccines, developed by China National Biotec Group (CNBG), are expected to enter the market as soon as this December, and two shots will cost less than 1,000 yuan (about 146 U.S. dollars), said Zhou Song, the company’s general legal counsel.

They are still undergoing phase three trials for safety and efficacy – usually the last step before regulatory approval – in more than 10 other countries, including the United Arab Emirates, Bahrain, Peru, Morocco, Argentina, and Jordan, since the epidemic has been basically put under control in China.

The two vaccine candidates, together with another one developed by Beijing-based Sinovac, have been approved for civilian emergency use after reliable results in phase one and phase two trials.

https://news.cgtn.com/news/2020-09-11/Hundreds-of-thousands-have-been-given-Chinese-COVID-19-vaccines-THnoo6BcFG/index.htmlHELP US SPREAD GOOD NEWS!

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China says has seen positive results in China-UAE phase 3 COVID-19 vaccine trials

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China and the United Arab Emirates have seen some positive results in their Phase III COVID-19 vaccine trials, Chinese foreign ministry spokesman Wang Wenbin told a news briefing in Beijing on Wednesday.

The United Arab Emirates on Monday granted emergency approval for use of a coronavirus vaccine, six weeks after human trials in the Gulf Arab state started.

https://www.reuters.com/article/us-health-coronavirus-emirates-vaccine-idUSKBN2670Y0HELP US SPREAD GOOD NEWS!

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Chinese vaccine ready for use in November, top scientist says

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Chinese people will have access to locally developed coronavirus vaccines as early as November or December, according to a top scientist from the Chinese Centre for Disease Control and Prevention (CDC).

Clinical trials of several vaccine candidates had been progressing smoothly and preparations were being made to go into mass production, Wu Guizhen, the CDC’s chief biosafety expert, said in a programme shown on Monday night by state broadcaster CCTV.

“I joined the experimental group and had a coronavirus shot in April,” Wu said. “I’ve felt quite good in the past few months, nothing abnormal. The process of inoculation did not cause any localised pain.”

According to the World Health Organisation (WHO), more than 30 vaccine candidates are undergoing clinical trials around the world. Of the nine to have reached the final, phase three, stage, five were developed in China.

Wu said she was optimistic about the vaccine candidates’ efficacy and safety.

“We expect them to remain effective for one to three years … [but] the results will need to be observed for a longer time.”

https://www.scmp.com/news/china/society/article/3101632/coronavirus-chinese-vaccine-ready-use-november-top-scientistHELP US SPREAD GOOD NEWS!

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Domestic air travel recovers in Wuhan, China

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Domestic air travel in Wuhan, the epicenter of the global coronavirus outbreak, has returned to pre-pandemic levels, authorities say.

The virus was first detected in Wuhan late last year and the city underwent a draconian 76-day lockdown as its hospitals struggled to deal with a tidal wave of cases that required the rapid construction of field hospitals to handle the overflow.

Since re-opening in early April, life has gradually returned to normal and numbers of domestic flights serving the city, as well as the number of passengers, had both fully recovered, according to the operator of Wuhan Tianhe International airport. It said 64,700 passengers were transported aboard 500 domestic flights on Friday.

The airport is preparing to eventually resume international passenger flights to destinations such as Seoul, Singapore, Kuala Lumpur and Jakarta, Qu Xiaoni, an airport representative was quoted as saying by the official Xinhua News Agency.

International cargo routes have already re-opened connecting the major industrial city and center of the Chinese auto industry with destinations such as Amsterdam and New Delhi.

China has gone almost a month without registering a new case of local transmission and on Sunday, the National Health Commission reported just 10 new cases, all of them imported.

https://apnews.com/453e6ba3bf9a4747326d6c1008300452HELP US SPREAD GOOD NEWS!

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