A single injection of the BioNTech / Pfizer vaccine produces a robust antibody response within weeks, according to Israeli data that could help determine whether scarce global supplies can be stretched by delaying second doses.
At the Rambam healthcare campus in northern Israel, 91% of the 1,800 doctors and nurses who received the two-dose vaccine showed a major presence of antibodies 21 days after their first injection, before receiving the vaccine. second dose, according to Michael Halberthal, chief director of the hospital. Another 2 percent showed a moderate presence of antibodies.
“If 93 percent had a significant response three weeks after the first injection, that raises a good question, namely that you could use the first injection on more people instead,” said Dr Halberthal.
At Sheba Medical Center, similar serological tests at different intervals showed that at least 50% of the staff had an antibody level ‘above the threshold’ two weeks after the first stroke, said Arnon Afek, associate managing director. the hospital chain.